Annihilation of Infectious Diseases is breathtaking, powerful, and a visual impact that takes the reader into an incredible journey to different forests in the third portion of the saga. The story is the first and a rare science-fiction piece never told before taking place in a futuristic digital and biological world. Several complex events are taking place giving the reader wondering what is going to happen next. Fantasy worlds of biomolecules in cellular processes, actions of enzymes, metabolism, transcription, and translation takes place where both superheroes Nextscienceman2100 and Nextsciencelady2100 conquer disease monsters using digitized medicine and the next scientific fields developed by Alpha Zeta on the galactic ship to bring health and humanity for society throughout the galaxy. Upgraded with higher technology, both of them make incredible defeats of predatory and infectious real female villains evoking both excitement and wonder. Female stalkers with leather cougar masks have their own hidden plans to target innocent male victims, but their plans will not always work as long as both superheroes go after them and bring them to justice. A mysterious villain is also hiding somewhere in the forest waiting to set off an intelligent bomb that is about to detonate and obliterate all biological forests. Both superheroes plan to annihilate these enemies up ahead once in for all in the twenty-second century.